Application

Compound 48/80 has been used:to stimulate hemocytes for histamine release for measurement in ELISA and flow cytometryto induce mast cell degranulationto induce anaphylactic activity, dermatitis, pruritis, inflammation in mice

Biochem/physiol Actions

Compound 48/80 (C 48/80) is a hypotensive agent, which promotes release of histamine. C 48/80 reduces the phagocytic ability of hemocytes in Styela plicata. C 48/80 promotes degranulation of mast cells. It Inhibits calmodulin, phospholipase C, endoplasmic reticulum (ER) Ca²⁺ ATPase and activates Gproteins.

General description

Compound 48/80, is the condensation product of N-methyl p-methoxyphenethylamine and formaldehyde.

Packaging

1 g in glass bottle

100, 250 mg in glass bottle

Preparation Note

Condensation product of N-methyl-p-methoxyphenethylamine with formaldehyde.