Analysis Note

single band by SDS-PAGE

General description

Recombinant, human β₂-microglobulin fused at the N-terminus to a His Tag™ sequence and expressed in E. coli. Subsequently cleaved with CNBr to remove the His Tag™ sequence. Extracellular protein that is non-covalently associated with the α-chains of class I MHC molecules. Used as a marker for various tumors and for kidney disease. The purified protein functions similarly to the native protein in in vitro models of amyloid fibril extension.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Other Notes

Sugg, S.V., et al. 1981. Proc. Natl. Acad. Sci. USA 78, 6613.Berggard, I., and Bearn, G. 1968. J. Biol. Chem. 243, 4095.

Packaging

1 mg in Plastic ampoule

Reconstitution

Following initial thaw, aliquot and freeze (-20°C).

Warning

Toxicity: Standard Handling (A)