Z3777-5MG Display Image

ZD7288 hydrate, >=98% (HPLC)

Code: Z3777-5MG D2-231

Application

ZD7288 hydrate has been used as Ih blocker to study its effect on neocortical tissue. It has been used as hyperpolarization-activated and cycl...

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£118.67 5MG
List Price

Application

ZD7288 hydrate has been used as Ih blocker to study its effect on neocortical tissue. It has been used as hyperpolarization-activated and cyclic nucleotide-gated (HCN)-channel blocker to test the involvement of HCN channels in the phototransduction pathway.

Biochem/physiol Actions

ZD7288 can block hippocampal synaptic plasticity.

Selective blocker of cation channel Ih; If blocker and sino-atrial node function modulator, blocks hyperpolarization-activated and cyclic nucleotide-gated (HCN) channels.

Features and Benefits

This compound was developed by AstraZeneca. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

This compound is featured on the Cyclic Nucleotide-Gated (CNG) and Hyperpolarization Activated Cyclic Nucleotide-Gated (HCN) Channels page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

This compound is a featured product for Cyclic Nucleotide research. Click here to discover more featured Cyclic Nucleotide products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

Packaging

5, 25 mg in glass bottle

SMILES stringO.Cl.CCN(c1ccccc1)C2=CC(=N/C)N(C)C(C)=N2
colorwhite to beige
assay≥98% (HPLC)
InChI keyNCEDDDWQLCMZQG-UPONXUSQSA-N
storage conditiondesiccated
originatorAstraZeneca
solubilityDMSO: 10 mg/mL, clear
InChI1S/C15H20N4.ClH.H2O/c1-5-19(13-9-7-6-8-10-13)15-11-14(16-3)18(4)12(2)17-15;;/h6-11H,5H2,1-4H3;1H;1H2/b16-14+;;
Quality Level100
storage temp.2-8°C
formpowder

Code
Description
Unit Size
List Price
Qty
Z3777-25MG
Unit:25MG
List Price: £441.07
Source:List Price
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