WH0005122M2-100UG Display Image

Monoclonal Anti-PCSK1 antibody produced in mouse, clone 3D2, purified immunoglobulin, buffered aqueous solution

Code: WH0005122M2-100UG D2-231

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to b...


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Your Price
£432.00 100UG

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

The protein encoded by this gene belongs to the subtilisin-like proprotein convertase family. The members of this family are proprotein convertases that process latent precursor proteins into their biologically active products. This encoded protein is a type I proinsulin-processing enzyme that plays a key role in regulating insulin biosynthesis. It is also known to cleave proopiomelanocortin, prorenin, proenkephalin, prodynorphin, prosomatostatin and progastrin. Mutations in this gene are thought to cause obesity. This encoded protein is associated with carcinoid tumors. The use of alternate polyadenylation sites has been found for this gene. Multiple alternatively spliced transcript variants have been described for this gene but their full length nature is not known. (provided by RefSeq)

Immunogen

PCSK1 (NP_000430, 652 a.a. ~ 753 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.SequenceGGRRDELEEGAPSEAMLRLLQSAFSKNSPPKQSPKKSPTAKLNIPYENFYEALEKLNKPSQLKDSEDSLYNDYVDVFYNTKPYKHRDDRLLQALVDILNEEN

Legal Information

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Physical form

Solution in phosphate buffered saline, pH 7.4

antibody formpurified immunoglobulin
antibody product typeprimary antibodies
biological sourcemouse
clone3D2, monoclonal
conjugateunconjugated
formbuffered aqueous solution
GenBank® accession no.NM_000439
Gene Informationhuman ... PCSK1(5122)
isotypeIgG3κ
Quality Level100
shipped indry ice
species reactivitymouse, rat, human
storage temp.−20°C
technique(s)indirect ELISA: suitable, western blot: 1-5 µg/mL, indirect immunofluorescence: suitable, immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable
UniProt accession no.P29120
Quantity
Est. Dispatch/Availability