SML1291-50MG Display Image

FROVATRIPTAN SUCCINATE MONOHYDRATE

Code: SML1291-50MG D2-231

Biochem/physiol Actions

Frovatriptan is a serotonin 5HT-1B/1D-receptor agonist used to treat migraine. Frovatriptan has high affinity for the 5-HT(1B) and 5-HT(1D) receptors ...


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£408.00 50MG
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Biochem/physiol Actions

Frovatriptan is a serotonin 5HT-1B/1D-receptor agonist used to treat migraine. Frovatriptan has high affinity for the 5-HT(1B) and 5-HT(1D) receptors while affinity for 5-HT receptors other than 5-HT(1B/1D) is substantially lower with a pEC50 value of 8.2 for the 5-HT1B receptor, compared to a pEC50 value of 6.2 for the 5-HT7 receptor.

During migraine condition, frovatriptan succinate monohydrate acts on extra cerebral, intracranial arteries and prevent excessive dilation of these vessels.

Packaging

10, 50 mg in glass bottle

assay≥97% (HPLC)
colorwhite to beige
formpowder
Gene Informationhuman ... HTR1B(3351), HTR1D(3352)
InChI keyCUETXFMONOSVJA-KLQYNRQASA-N
InChI1S/C14H17N3O.C4H6O4.H2O/c1-16-9-3-5-13-11(7-9)10-6-8(14(15)18)2-4-12(10)17-13;5-3(6)1-2-4(7)8;/h2,4,6,9,16-17H,3,5,7H2,1H3,(H2,15,18);1-2H2,(H,5,6)(H,7,8);1H2/t9-;;/m1../s1
Quality Level100
SMILES stringOC(CCC(O)=O)=O.NC(C(C=C1)=CC2=C1NC3=C2C[C@H](NC)CC3)=O.O
solubilityH2O: 20 mg/mL, clear
storage conditiondesiccated
storage temp.2-8°C
Code
Description
Unit Size
List Price
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SML1291-10MG
FROVATRIPTAN SUCCINATE MONOHYDRATE

Unit:10MG
List Price: £101.00
Source:List Price
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Cas Number158930-17-7
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