Application

Darifenacin hydrobromide has been used to inject experimental animals.

Biochem/physiol Actions

Darifenacin hydrobromide is an antispasmodic muscarinic antagonist, selective for blocking the M3 muscarinic acetylcholine receptor.

Darifenacin hydrobromide is an antispasmodic muscarinic antagonist, selective for blocking the M3 muscarinic acetylcholine receptor, which is primarily responsible for bladder muscle contractions. Darifenacin hydrobromide has 9 and 12-fold greater affinity for M3 compared to M1 and M5, respectively, and 59-fold greater affinity for M3 compared to both M2 and M4. Darifenacin is used clinically to treat urinary incontinence and overactive bladder syndrome.

Features and Benefits

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General description

Darifenacin is a muscarinic receptor antagonist. It is an extended release tablet that has 7.5mg or 15mg darifenacin as its hydrobromide salt.

Packaging

10, 50 mg in glass bottle