Application
Teriflunomide has been used as a dihydroorotate dehydrogenase (DHODH) inhibitor.
Biochem/physiol Actions
Teriflunomide is an orally available anti-inflammatory immunomodulator. It blocks the activity of dihydroorotate dehydrogenase, preventing pyrimidine synthesis and T and B cell proliferation and function. Teriflunomide has been used to treat rheumatoid arthritis and was recently approved for multiple sclerosis.
Packaging
10, 50 mg in glass bottle
This product has met the following criteria: