SML0724-1MG Display Image

Bikaverin, from Fusarium subglutinans, >=98% (HPLC)

Code: SML0724-1MG D2-231

Biochem/physiol Actions

Bikaverin is a red pigment with a polyketide tetracyclic benzoxanthone structure. Bikaverin has an antibiotic activity against some protozoa and fungi...

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£272.00 1MG
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Biochem/physiol Actions

Bikaverin is a red pigment with a polyketide tetracyclic benzoxanthone structure. Bikaverin has an antibiotic activity against some protozoa and fungi and also inhibits Succinate- and NAD-linked respiration in rat mitochondria at 20 mg/mL. At higher concentrations (50 mg/mL) it acts as an oxidative phosphorylation uncoupling agent of tumor cells and isolated rat liver mitochondria. Bikaverin demonstrates antitumor activity on Erlich ascites carcinoma (EAC), leukemia and sarcoma cells.

Reconstitution

Soluble in DMSO (0.5 mg/mL, may require sonication and heating). For further dilution, water based solutions can be used. Chloroform (0.5 mg/mL) and dichloromethane (0.5 mg/mL).

InChI1S/C20H14O8/c1-7-4-8(26-2)5-10-12(7)17(23)15-18(24)13-9(21)6-11(27-3)16(22)14(13)19(25)20(15)28-10/h4-6,24-25H,1-3H3
Quality Level200
solubilitydichloromethane: 0.5 mg/mL
solubilityDMSO: 0.5 mg/mL (may require sonication and heating)
solubilitychloroform: 0.5 mg/mL
assay≥98% (HPLC)
storage temp.−20°C
InChI keyZOQMSOSJEWBMHP-UHFFFAOYSA-N
biological sourceFusarium subglutinans
formpowder

Cas Number33390-21-5
Hazard Class6.1
Un Number2811
Pack Group3