Biochem/physiol Actions

Linker for activation of T cells (LAT) indicate an important role of immune molecules in the growing brain. It also helps in the development, activation and maintenance of T cells. Mutations in LAT result in severe combined immunodeficiency. It also act as a bridge between T cell-specific and general signaling pathways.

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General description

Anti-LAT Antibody detects endogenous levels of total LAT protein.

Linker for activation of T cells (LAT) is a transmembrane adapter molecule. It is located on human chromosome 16p11.2. It is present in activated T cells.

Immunogen

The antiserum was produced against synthesized peptide derived from human LAT.Immunogen Range: 86-135

Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.