Biochem/physiol Actions
Fibroblast growth factor receptor 2 (FGFR2) mutations show poor clinical diagnosis in endometrioid endometrial cancer. The FGFR2 gene participates in directional epithelial-mesenchymal signaling in the endometrium. It is essential for placentation and limb induction.
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General description
Fibroblast growth factor receptor 2 (FGFR2), a membrane-spanning tyrosine kinase belongs to the fibroblast growth factor (FGF) family. It is expressed in epithelium, developing central nervous system and in bone rudiments. It is located on human chromosome 10q26.
Anti-FGFR2 Antibody detects endogenous levels of total FGFR2 protein.
Immunogen
The antiserum was produced against synthesized peptide derived from human FGFR2.Immunogen Range: 471-520
Physical form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
This product has met the following criteria: