SAB4500888-100UG Display Image

Anti-FGFR3 antibody produced in rabbit, approx. 1 mg/mL, affinity isolated antibody, buffered aqueous solution

Code: SAB4500888-100UG D2-231

Application

Anti-FGFR3 antibody has been used in immunohistochemistry.

Biochem/physiol Actions

Germline mutations in FGFR3 (fibroblast growth fac...

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£394.00 100UG
List Price

Application

Anti-FGFR3 antibody has been used in immunohistochemistry.

Biochem/physiol Actions

Germline mutations in FGFR3 (fibroblast growth factor receptor 3) results in autosomal dominant skeletal dysplasias like achondroplasia (ACH), thanatophoric dysplasia (TD) and hypochrondroplasia (HCH). The gene also controls cellular activity.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Features and Benefits

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General description

Anti-FGFR3 Antibody detects endogenous levels of total FGFR3 protein.

FGFR3 (fibroblast growth factor receptor 3) belongs to the fibroblast growth factor receptor (Fgfr) family of proteins. It has 19 exons, an extracellular ligand binding domain, a transmembrane domain and an intracellular tyrosine kinase domain. It is located on human chromosome 4p16.3.

Immunogen

The antiserum was produced against synthesized peptide derived from human FGFR3.Immunogen Range: 131-180

Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

clonepolyclonal
antibody formaffinity isolated antibody
UniProt accession no.P22607
concentration~1 mg/mL
application(s)immunohistochemistry: 1:50-1:100
application(s)ELISA: 1:10000
application(s)western blot: 1:500-1:1000
storage temp.−20°C
Quality Level100
NCBI accession no.P22607
shipped inwet ice
antibody product typeprimary antibodies
biological sourcerabbit
Gene Informationhuman ... FGFR3(2261)
conjugateunconjugated
mol wtantigen 87 kDa
species reactivityrat, human, mouse
formbuffered aqueous solution