SAB1405882-50UG Display Image

Anti-GNAQ antibody produced in mouse, purified immunoglobulin, buffered aqueous solution

Code: SAB1405882-50UG D2-231

General description

Guanine nucleotide-binding proteins are a family of heterotrimeric proteins that couple cell surface, 7-transmembrane domain receptors to intracellular si...

read more

£371.00 50UG
List Price

General description

Guanine nucleotide-binding proteins are a family of heterotrimeric proteins that couple cell surface, 7-transmembrane domain receptors to intracellular signaling pathways. Receptor activation catalyzes the exchange of GTP for GDP bound to the inactive G protein alpha subunit resulting in a conformational change and dissociation of the complex. The G protein alpha and beta-gamma subunits are capable of regulating various cellular effectors. Activation is terminated by a GTPase intrinsic to the G-alpha subunit. G-alpha-q is the alpha subunit of one of the heterotrimeric GTP-binding proteins that mediates stimulation of phospholipase C-beta (MIM 600230).[supplied by OMIM

Immunogen

GNAQ (NP_002063.2, 1 a.a. ~ 359 a.a) full-length human protein.SequenceMTLESIMACCLSEEAKEARRINDEIERQLRRDKRDARRELKLLLLGTGESGKSTFIKQMRIIHGSGYSDEDKRGFTKLVYQNIFTAMQAMIRAMDTLKIPYKYEHNKAHAQLVREVDVEKVSAFENPYVDAIKSLWNDPGIQECYDRRREYQLSDSTKYYLNDLDRVADPAYLPTQQDVLRVRVPTTGIIEYPFDLQSVIFRMVDVGGQRSERRKWIHCFENVTSIMFLVALSEYDQVLVESDNENRMEESKALFRTIITYPWFQNSSVILFLNKKDLLEEKIMYSHLVDYFPEYDGPQRDAQAAREFILKMFVDLNPDSDKIIYSHFTCATDTENIRFVFAAVKDTILQLNLKEYNLV

Physical form

Solution in phosphate buffered saline, pH 7.4

clonepolyclonal
application(s)western blot: 1 µg/mL
UniProt accession no.P50148
shipped indry ice
antibody formpurified immunoglobulin
storage temp.−20°C
Quality Level100
antibody product typeprimary antibodies
NCBI accession no.NM_002072
conjugateunconjugated
biological sourcemouse
mol wtantigen ~42.1 kDa
species reactivityhuman
Gene Informationhuman ... GNAQ(2776)
formbuffered aqueous solution