SAB1404879-100UG Display Image

Monoclonal Anti-RNPS1 antibody produced in mouse, clone 7G8, purified immunoglobulin, buffered aqueous solution

Code: SAB1404879-100UG D2-231

General description

This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveill...

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£371.00 100UG
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General description

This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein binds to the mRNA and remains bound after nuclear export, acting as a nucleocytoplasmic shuttling protein. This protein contains many serine residues. Two splice variants have been found for this gene; both variants encode the same protein. (provided by RefSeq)

Immunogen

RNPS1 (NP_006702, 158 a.a. ~ 239 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.SequencePKPTKVHIGRLTRNVTKDHIMEIFSTYGKIKMIDMPVERMHPHLSKGYAYVEFENPDEAEKALKHMDGGQIDGQEITATAVL

Physical form

Solution in phosphate buffered saline, pH 7.4

mol wtantigen ~35.13 kDa
shipped indry ice
isotypeIgG2aκ
antibody formpurified immunoglobulin
application(s)indirect ELISA: suitable
application(s)western blot: 1-5 µg/mL
UniProt accession no.Q15287
storage temp.−20°C
Quality Level100
antibody product typeprimary antibodies
conjugateunconjugated
biological sourcemouse
species reactivityhuman
formbuffered aqueous solution
Gene Informationhuman ... RNPS1(10921)
NCBI accession no.NM_006711
clone7G8, monoclonal