SAB1403409-100UG Display Image

Monoclonal Anti-ABCC11 antibody produced in mouse, clone 4H6, purified immunoglobulin, buffered aqueous solution

Code: SAB1403409-100UG D2-231

General description

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules acros...

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£371.00 100UG
List Price

General description

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This ABC full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. The product of this gene participates in physiological processes involving bile acids, conjugated steroids, and cyclic nucleotides. In addition, a SNP in this gene is responsible for determination of human earwax type. This gene and family member ABCC12 are determined to be derived by duplication and are both localized to chromosome 16q12.1. Multiple alternatively spliced transcript variants have been described for this gene. (provided by RefSeq)

Immunogen

ABCC11 (NP_115972.2, 433 a.a. ~ 532 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.SequenceFVPIAVKGLTNSKSAVMRFKKFFLQESPVFYVQTLQDPSKALVFEEATLSWQQTCPGIVNGALELERNGHASEGMTRPRDALGPEEEGNSLGPELHKINL

Physical form

Solution in phosphate buffered saline, pH 7.4

mol wtantigen ~37.11 kDa
Gene Informationhuman ... ABCC11(85320)
shipped indry ice
isotypeIgG2aκ
antibody formpurified immunoglobulin
application(s)indirect ELISA: suitable
application(s)western blot: 1-5 µg/mL
application(s)immunofluorescence: suitable
NCBI accession no.NM_032583
storage temp.−20°C
Quality Level100
antibody product typeprimary antibodies
UniProt accession no.Q96J66
conjugateunconjugated
clone4H6, monoclonal
biological sourcemouse
species reactivityhuman
formbuffered aqueous solution