SAB1403400-100UG Display Image

Monoclonal Anti-KIRREL3, (C-terminal) antibody produced in mouse, clone 3A12, purified immunoglobulin, buffered aqueous solution

Code: SAB1403400-100UG D2-231

General description

The protein encoded by this gene is a member of the nephrin-like protein family. These proteins are expressed in fetal and adult brain, and also in podocy...

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£371.00 100UG
List Price

General description

The protein encoded by this gene is a member of the nephrin-like protein family. These proteins are expressed in fetal and adult brain, and also in podocytes of kidney glomeruli. The cytoplasmic domains of these proteins interact with the C-terminus of podocin, also expressed in the podocytes, cells involved in ensuring size- and charge-selective ultrafiltration. Mutations in this gene are associated with mental retardation autosomal dominant type 4 (MRD4). Alternatively spliced transcript variants encoding different isoforms have been found for this gene

Immunogen

KIRREL3 (NP_115920.1, 679 a.a. ~ 778 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.SequenceYSTLSGQGRLYDYGQRFVLGMGSSSIELCEREFQRGSLSDSSSFLDTQCDSSVSSSGKQDGYVQFDKASKASASSSHHSQSSSQNSDPSRPLQRRMQTHV

Physical form

Solution in phosphate buffered saline, pH 7.4

mol wtantigen ~37.11 kDa
shipped indry ice
isotypeIgG2aκ
antibody formpurified immunoglobulin
application(s)indirect ELISA: suitable
application(s)western blot: 1-5 µg/mL
storage temp.−20°C
Quality Level100
Gene Informationhuman ... KIRREL3(84623)
antibody product typeprimary antibodies
conjugateunconjugated
clone3A12, monoclonal
biological sourcemouse
NCBI accession no.NM_032531
species reactivityhuman
formbuffered aqueous solution
UniProt accession no.Q8IZU9