N-Allyl-(±)-SKF-38393 hydrobromide was used to study dopaminergic signaling in neurons of developing mice and cardiomyocytes injured by oxidants.
N-Allyl-(±)-SKF-38393 hydrobromide is a selective agonist of D1/D5 dopamine receptors. It mimics the physiological action of dopamine and enhances cognition, memory and learning. It decreases the age-related decline in long-term potentiation of mouse hippocampus. SKF-38393 increases the D1-mediated locomotion in rats.