P9703-100MG Display Image

Pimaricin, from Streptomyces chattanoogensis, >=95% (HPLC)

Code: P9703-100MG D2-231

Application

Pimaricin is an amphoteric antibiotic from Streptomyces chattanoogensis. It is used for a variety of fungal infections, mainly topically. It is used as a...


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£920.00 100MG
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Application

Pimaricin is an amphoteric antibiotic from Streptomyces chattanoogensis. It is used for a variety of fungal infections, mainly topically. It is used as an ergosterol and cholesterol binding agent to study lipid bilayer dynamics, especially in fungal cells. Pimaricin is used as a fungicide in agar media. It is used to study the pleitropic regulator AdpAch and the gamma-butyrolactone regulatory system of Streptomyces chattanoogensis.

Biochem/physiol Actions

An antifungal polyene macrolide that binds specifically to ergosterol and blocks fungal growth. However, unlike nysatin and filipin, pimaricin does not change the permeability of the plasma membrane

General description

Chemical structure: macrolide

Other Notes

Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature: 2 - 8 °C. Light sensitive.

Packaging

50, 100 mg in glass bottle

25 mg in poly bottle

antibiotic activity spectrumfungi
application(s)agricultureenvironmental
assay≥95% (HPLC)
biological sourceStreptomyces chattanoogensis
formpowder, lyophilized powder
InChI keyNCXMLFZGDNKEPB-FFPOYIOWSA-N
InChI1S/C33H47NO13/c1-18-10-8-6-4-3-5-7-9-11-21(45-32-30(39)28(34)29(38)19(2)44-32)15-25-27(31(40)41)22(36)17-33(42,47-25)16-20(35)14-24-23(46-24)12-13-26(37)43-18/h3-9,11-13,18-25,27-30,32,35-36,38-39,42H,10,14-17,34H2,1-2H3,(H,40,41)/b4-3+,7-5+,8-6+,11-9+,13-12+/t18-,19-,20+,21+,22+,23-,24-,25+,27-,28+,29-,30+,32+,33-/m1/s1
mode of actioncell membrane | interferes
Quality Level300
SMILES stringC[C@@H]1CC=CC=CC=CC=C[C@@H](C[C@@H]2O[C@](O)(C[C@@H](O)C[C@H]3O[C@@H]3C=CC(=O)O1)C[C@H](O)[C@H]2C(O)=O)O[C@@H]4O[C@H](C)[C@@H](O)[C@H](N)[C@@H]4O
solubility0.1% formic acid in methanol: soluble 1 mg/mL
storage temp.2-8°C
Code
Description
Unit Size
List Price
Qty
P9703-25MG
Pimaricin, from Streptomyces chattanoogensis, >=95% (HPLC)

Unit:25MG
List Price: £305.00
Source:List Price
ADD
P9703-50MG
Pimaricin, from Streptomyces chattanoogensis, >=95% (HPLC)

Unit:50MG
List Price: £528.00
Source:List Price
ADD
Cas Number7681-93-8
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