P9564-100MG Display Image

Phleomycin from Streptomyces verticillus, powder

Code: P9564-100MG D2-231

Biochem/physiol Actions

Phleomycin is a structurally related form of the antibiotic, bleomycin. Phleomycin blocks S-phase entry in the cell cycle. While phleomycin can damage...

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£863.24 100MG
List Price

Biochem/physiol Actions

Phleomycin is a structurally related form of the antibiotic, bleomycin. Phleomycin blocks S-phase entry in the cell cycle. While phleomycin can damage DNA, like bleomycin, it is not used as an anticancer agent, but rather as a selection agent. The RAD6 DNA repair gene is essential for phleomycin resistance in mutant yeast.

Features and Benefits

This compound is a featured product for Apoptosis research. Click here to discover more featured Apoptosis products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

General description

Chemical structure: glycopeptide

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

antibiotic activity spectrumfungi
Quality Level200
storage temp.2-8°C
InChI1S/C51H75N17O21S2/c1-16-29(65-41(68-38(16)54)21(8-27(53)72)60-9-20(52)39(55)78)44(82)67-31(34(22-10-58-15-61-22)88-49-50(5,36(76)33(74)25(11-69)87-49)89-47-37(77)51(85,48(57)84)35(75)26(12-70)86-47)45(83)62-18(3)32(73)17(2)42(80)66-30(19(4)71)43(81)59-7-6-28-63-24(14-90-28)46-64-23(13-91-46)40(56)79/h10,13,15,17-18,20-21,24-26,30-37,47,49,60,69-70,73-77,85H,6-9,11-12,14,52H2,1-5H3,(H2,53,72)(H2,55,78)(H2,56,79)(H2,57,84)(H,58,61)(H,59,81)(H,62,83)(H,66,80)(H,67,82)(H2,54,65,68)/t17?,18?,20?,21?,24?,25-,26?,30?,31?,32?,33+,34?,35-,36-,37-,47-,49-,50-,51+/m0/s1
colorblue
Mode of actionDNA synthesis | interferes
formpowder
shelf life2 yr
InChI keyQRBLKGHRWFGINE-UGWAGOLRSA-N

Code
Description
Unit Size
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P9564-25MG
Unit:25MG
List Price: £258.34
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P9564-5MG
Unit:5MG
List Price: £75.19
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Cas Number11006-33-0