Application

Nω-Nitro-L-arginine methyl ester hydrochloride has been used:to study the effects of brain-derived neurotrophic factor against neurotoxicity in rat cortical neuronsto study its effect on far-infrared (FIR) enhanced microcirculation of rat skin to study its effect on leptin-induced regulation of myokine fibronectin type III domain containing five/irisin in murine myocytes and fat cellsto study its effect on the levels of arginine vasopressin and neuronal nitric oxide synthase mRNA levels in hypothalamic paraventricular nucleus and supraoptic nucleus of rat

Biochem/physiol Actions

An analog of arginine that inhibits NO production. It has multiple effects on the vascular system. Inhibits relaxation induced by acetylcholine and induces an increase in arterial blood pressure. Abolishes lecithinized superoxide dismutase induced vasodilation when used to pretreat aortic ring preparations of mice. Induces leukocyte adhesion and increases microvascular fluid and protein fluxes and permeability. It has also been used in many studies of learning and memory.

Packaging

250 mg in poly bottle

1, 5, 10, 25 g in poly bottle