Application

N-Nitroso-N-ethylurea has been used as a mutation-inducing agent.

Biochem/physiol Actions

DNA alkylating agent that is carcinogenic in many animal species. Induces benign and malignant tumors of numerous types, including the nervous tissue, stomach, esophagus, pancreas, respiratory tract, intestine, lymphoreticular tissues, skin, and kidney.

Caution

Injecting any compatible solvent permits preparation of any desired strength solution without exposure.

Legal Information

Isopac is a registered trademark of Sigma-Aldrich Co. LLC

Packaging

1 g in serum bottle

Packaged in a 100 mL serum bottle with silicon/PTFE septum and aluminum tear seal.1 vial contains 1 g of material calculated on anhydrous basis.

Reconstitution

Dissolving the contents in 100 mL of solvent yields a 1% solution.