N3290-25MG Display Image

NKH 477, >=98% (HPLC), powder

Code: N3290-25MG D2-231

Biochem/physiol Actions

NKH 477 is a potent, orally active adenylyl cyclase activator. It is a water soluble derivative of forskolin, and dose dependentyl increases cAMP and ...


read more

Your Price
£529.00 25MG
REQUEST

Biochem/physiol Actions

NKH 477 is a potent, orally active adenylyl cyclase activator. It is a water soluble derivative of forskolin, and dose dependentyl increases cAMP and blocks potassium-induced contraction concetrations in smooth muscle strips (IC50 = 80 nM). NKH 477 causes relaxation of histamine treated guinea pig smooth muscle (IC50 = 32 nM).

Features and Benefits

This compound is a featured product for Cyclic Nucleotide research. Click here to discover more featured Cyclic Nucleotide products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

Packaging

5, 25 mg in glass bottle

Preparation Note

A clear to slightly hazy solution is possible.

assay≥98% (HPLC)
colorwhite to beige
formpowder
InChI keyVIRRLEDAYYYTOD-YHEOSNBFSA-N
InChI1S/C27H43NO8.ClH/c1-10-24(5)15-18(31)27(33)25(6)17(30)11-13-23(3,4)21(25)20(35-19(32)12-14-28(8)9)22(34-16(2)29)26(27,7)36-24;/h10,17,20-22,30,33H,1,11-15H2,2-9H3;1H/t17-,20-,21-,22-,24-,25-,26+,27-;/m0./s1
Quality Level100
SMILES stringCl.CN(C)CCC(=O)O[C@@H]1[C@H](OC(C)=O)[C@@]2(C)O[C@](C)(CC(=O)[C@]2(O)[C@@]3(C)[C@@H](O)CCC(C)(C)[C@H]13)C=C
solubilityH2O: 3 mg/mL, clear to slightly hazy (warmed)
storage conditiondesiccated
storage temp.2-8°C
Code
Description
Unit Size
List Price
Qty
N3290-5MG
NKH 477, >=98% (HPLC), powder

Unit:5MG
List Price: £134.00
Source:List Price
ADD
Cas Number138605-00-2
Hazard Class6.1
Un Number2811
Pack Group2
This product has met the following criteria: