Application

IgG1, Kappa from murine myeloma has been used in: chromatin immunoprecipitation (ChIP)immunofluorescenceimmunocaptureenzyme immunoassayimmunohistochemistry

Biochem/physiol Actions

IgG1 is the most abundant and its deficiency results in hypogammaglobulinemia. IgG antibody have enormous therapeutic potential and the Fc region is involved the development of therapeutic antibody.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

Immunoglobulins (Igs) belongs to the immunoglobulin super-family. IgG is the abundant immunoglobulin in human serum. The four classes of IgG can be IgG1, IgG2, IgG3 and IgG4.

Mammalian immunoglobins contain either lambda or kappa light chains.

Physical form

Solution in 0.02 M Tris buffered saline, pH 8.0, containing 0.02% sodium azide

Specificity

Specificity is determined by mouse monoclonal isotyping strips. The purified immunoglobulin preparation is non-reactive with mouse IgA, IgM, IgG2a, IgG2b, or IgG3.