L3410-.2ML Display Image

Anti-Leptin antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution

Code: L3410-.2ML D2-231

Application

Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.Western Blotting (1 paper)

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Application

Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.Western Blotting (1 paper)

Biochem/physiol Actions

Leptin is a hormone secreted by adipocytes and regulates energy homeostasis, inflammation and neuroendocrine processes, synaptic formation and memory condensation. The physiological effects of leptin are mediated by leptin receptors, ObR and LepR. Leptin is the key regulator of obesity and acts directly on neuronal networks to regulate feeding, metabolism, gastric mobility and energy homeostasis. The pathways that mediate the effect of leptin are JAK/STAT, PI3K and JNK.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Immunogen

synthetic peptide corresponds to the amino terminal (amino acid residues 22-40) of human/mouse leptin.

Physical form

Solution in phosphate buffered saline containing 1% bovine serum albumin and 15 mM sodium azide.

Preparation Note

The antibody is affinity isolated on peptide-agarose.

Quality Level200
clonepolyclonal
antibody product typeprimary antibodies
biological sourcerabbit
antibody formaffinity isolated antibody
conjugateunconjugated
application(s)microarray: suitable
application(s)western blot: 1:5,000 using human recombinant leptin
application(s)indirect ELISA: 1:1,000 using human or mouse recombinant leptin
species reactivityhuman, mouse
shipped indry ice
UniProt accession no.P41159
Gene Informationhuman ... LEP(3952)

mouse ... Lep(16846)

formbuffered aqueous solution
storage temp.20C