Analysis Note
Biological activity is measured by its ability to inhibit DEVD-afc cleavage in cell extracts activated by cytochrome c and dATP.
Biochem/physiol Actions
Livin β/ML-IAP, a member of the inhibitor of apoptosis (IAP) protein family, inhibits the activation of caspase 9 in cell extracts incubated with cytochrome c and dATP.
Physical form
Solution in 25 mM Hepes, pH 7.5, 0.1 M sodium chloride, and 1 mM dithiothreitol.
This product has met the following criteria: