L0669-500UG Display Image

Monoclonal Anti-Leukemia Inhibitory Factor antibody produced in mouse, clone 9824, purified immunoglobulin, lyophilized powder

Code: L0669-500UG D2-231

Biochem/physiol Actions

Leukemia inhibitory factor (LIF) is a pleotrophic glycoprotein that belongs to the IL-6 family of cytokines. It is secreted by many cell types such as...

read more

£768.00 500UG
List Price

Biochem/physiol Actions

Leukemia inhibitory factor (LIF) is a pleotrophic glycoprotein that belongs to the IL-6 family of cytokines. It is secreted by many cell types such as, fibroblasts, macrophages, T cells, monocytes, liver cells, osteoblasts and cells of endometrium. A variety of signal transduction pathways are triggered in response to LIF including ERK/MAPK, JAK1, PI3K, STAT3, Jun-c Fos and NF-?B. The various functions of LIF include proliferation of adult human T cells, maintenance of pluripotency of embryonic stem cells and inhibition of leukemic cell differentiation.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Immunogen

purified, E. coli-derived recombinant human leukemia inhibitory factor.

Physical form

Lyophilized from a 0.2 µm filtered solution in phosphate buffered saline with 5% trehalose.

application(s)immunohistochemistry: 25 µg/mL
application(s)western blot: 1-2 µg/mL
application(s)capture ELISA: 2-4 µg/mL
application(s)neutralization: suitable
Gene Informationhuman ... LIF(3976)
antibody formpurified immunoglobulin
formlyophilized powder
clone9824, monoclonal
storage temp.−20°C
Quality Level100
antibody product typeprimary antibodies
conjugateunconjugated
biological sourcemouse
UniProt accession no.P15018
species reactivityhuman