Application

Anti-Human IgA (α-chain specific) antibody is suitable for Ouchterlony double diffusion. The antibody was used for IgA quantification by ELISA in various studies. Antibody dilution of 1:4000 was used for passive hemagglutination inhibition assay.

Goat polyclonal anti-human IgA (α-chain specific) antibody may be used to locate and identify the α-chain of human IgA by immunocytochemical and immunohistochemical (IHC) techniques.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

IgA antibody is secretory antibody and is present abundantly in mucous linings of gastrointestinal, respiratory and genitourinary tracts, tears and saliva. Thus secretory IgA contributes to the humoral defense mechanism against the pathogens on mucosal surfaces Anti-Human IgA (α-chain specific) antibody specifically recognizes human IgA.

Specificity for the α-chain of human IgA is determined by Ouchterlony Double Diffusion (ODD). The antibody preparation is specific for human IgA when tested against purified human IgA, IgG, IgM, Bence Jones kappa and Bence Jones λ myeloma proteins.

Immunoglobulin A (IgA) is the primary antibody involved in mucosal immunity. It is identified by the presence of α-type heavy chains. IgA which is composed of two subclasses IgA1 and IgA2 can exist in a dimeric secretory form found in mucous secretions.

Immunogen

Purified human IgA

Physical form

Lyophilized from 0.01 M sodium phosphate, 0.015 M sodium chloride, pH 7.2