HPA056337-25UL Display Image


Code: HPA056337-25UL D2-231


Anti-KLHL24 antibody produced in rabbit has been used in the detection of KLHL24 in human embryonic kidney 293 cells by western blotting.

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Anti-KLHL24 antibody produced in rabbit has been used in the detection of KLHL24 in human embryonic kidney 293 cells by western blotting.

All Prestige Antibodies Powered by Atlas Antibodies are developed and validated by the Human Protein Atlas (HPA) project and as a result, are supported by the most extensive characterization in the industry. The Human Protein Atlas project can be subdivided into three efforts: Human Tissue Atlas, Cancer Atlas, and Human Cell Atlas. The antibodies that have been generated in support of the Tissue and Cancer Atlas projects have been tested by immunohistochemistry against hundreds of normal and disease tissues and through the recent efforts of the Human Cell Atlas project, many have been characterized by immunofluorescence to map the human proteome not only at the tissue level but now at the subcellular level. These images and the collection of this vast data set can be viewed on the Human Protein Atlas (HPA) site by clicking on the Image Gallery link. We also provide Prestige Antibodies® protocols and other useful information.

Biochem/physiol Actions

Kelch-like family member 24 (KLHL24) plays a key role in regulation of cytoskeleton interactions, ubiquitination and gene expression. Mutation in KLHL24 impairs intermediary filament organisation which inturn impacts skin integrity. Mutations of KLHL24 also results in a N-terminal truncated protein which is associated with skin disorder, epidermolysis bullosa simplex.


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Features and Benefits

Prestige Antibodies® are highly characterized and extensively validated antibodies with the added benefit of all available characterization data for each target being accessible via the Human Protein Atlas portal linked just below the product name at the top of this page. The uniqueness and low cross-reactivity of the Prestige Antibodies® to other proteins are due to a thorough selection of antigen regions, affinity purification, and stringent selection. Prestige antigen controls are available for every corresponding Prestige Antibody and can be found in the linkage section.Every Prestige Antibody is tested in the following ways: IHC tissue array of 44 normal human tissues and 20 of the most common cancer type tissues. Protein array of 364 human recombinant protein fragments.

General description

Kelch-like family member 24 (KLHL24) belongs to kelch-like (KLHL) protein family and has N-terminal broad-complex proteins (BTB) domain, a central BACK domain (for BTB and C-terminal Kelch) followed by C-terminal Kelch domains.


kelch-like 24 (Drosophila) recombinant protein epitope signature tag (PrEST)

Legal Information

Prestige Antibodies is a registered trademark of Sigma-Aldrich Co. LLC


Corresponding Antigen APREST85393.

Physical form

Solution in phosphate buffered saline, pH 7.2, containing 40% glycerol and 0.02% sodium azide.

antibody formaffinity isolated antibody
antibody product typeprimary antibodies
biological sourcerabbit
formbuffered aqueous glycerol solution
Gene Informationhuman ... KLHL24(54800)
packagingantibody small pack of 25 µL
product linePrestige Antibodies® Powered by Atlas Antibodies
Quality Level100
shipped inwet ice
species reactivityhuman
storage temp.−20°C
technique(s)immunohistochemistry: 1:50-1:200
UniProt accession no.Q6TFL4
Unit Size
List Price
List Price: £451.00
Source:List Price
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