Application

Fetuin from fetal bovine serum has been used:as a standard glycoprotein in matrix-assisted laser desorption/ionization-mass spectrometry (MALDI-MS) and high-performance liquid chromatography-fluorescence detection analysis (HPLC-FLD)as a ligand in carbohydrate binding assay of pertussis toxin vaccinein the synthesis of fetuin-A conjugated gold nanoparticles (F-GNPs) for drug carrier studies

Biochem/physiol Actions

In humans, polymorphism in the fetuin gene is implicated in type 2 diabetes mellitus and modulates adipocyte functionality. Elevated level of fetuin is observed in obesity and nonalcoholic fatty liver diseases (NAFLD). Fetuin is a potential marker in clinical diagnosis of metabolic disorders.

General description

Fetuin is an abundant glycosylated protein from fetal bovine serum and functions as a transport and storage protein. It is also called the α2-Heremans-Schmid glycoprotein (AHSG) and corresponds to a molecular weight of 64 kDa. It belongs to the statin family and is synthesized principally in the liver and partially in the kidneys, placenta and the tongue.

Packaging

1 g in glass bottle

25, 100, 250 mg in glass bottle

Preparation Note

Further processing of F2379 by gel filtration.