Application

Chlorisondamine diiodide has been used:as a nicotinic receptor antagonist to test its effect on trinitrobenzene sulfonic acid (TNBS)-induced colitisas an irreversible nicotinic acetylcholine(nAChR) blocker to pre-treat brain samples to test its effect on cytochrome P450 2B (CYP2B) inductionas a ganglionic blocker to test its effect on regulating corticosterone levels in rat with chronic stress

Biochem/physiol Actions

Irreversible, long-lasting nicotinic acetylcholine receptor antagonist.

Chlorisondamine diiodide mediates ganglionic and central blockade.

Features and Benefits

This compound is featured on the Acetylcholine Receptors (Nicotinic) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

Packaging

10, 50 mg in glass bottle