B2188-200UL Display Image

Anti-BPI (61-75) antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution

Code: B2188-200UL D2-231


Anti-BPI (61-75) antibody produced in rabbit has been used in immunoprecipitation.

Biochem/physiol Actions

BPI gene encodes a membran...

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£403.00 200UL


Anti-BPI (61-75) antibody produced in rabbit has been used in immunoprecipitation.

Biochem/physiol Actions

BPI gene encodes a membrane associated bactericidal permeability increasing protein. BPI possesses high affinity for lipopolysaccharide. It has antimicrobial activity against gram-negative organisms and is essential constituent of the innate immune system for destroying the microbes as well as modulates subsequent adaptive immune responses. The amino-terminal of BPI is responsible for antimicrobial cytotoxicity and endotoxin-neutralization. The carboxyl-terminal is mainly for BPI-dependent transfer of Gram-negative bacteria and cell free endotoxin-rich particles to specific host cells. Mutation in BPI gene or a decrease of plasma BPI level may lead to chronic obstructive pulmonary disease (acute pneumonia and cystic fibrosis).


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General description

BPI (Bactericidal permeability-increasing protein) gene is mapped on to human chromosome 20q11.23. It belongs to the family of lipid-transfer proteins. BPI is mainly present in the granules of neutrophils and on the surface of neutrophils and monocytes.


synthetic peptide corresponding to amino acids 61-75 of human BPI

Physical form

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.

Target description

BPI (61-75), bactericidal/permeability-increasing protein, encodes a lipopolysaccharide binding protein. It is associated with human neutrophil granules and has bactericidal activity on gram-negative organisms.

antibody formIgG fraction of antiserum
antibody product typeprimary antibodies
biological sourcerabbit
formbuffered aqueous solution
Gene Informationhuman ... BPI(671)
mol wtantigen ~54 kDa
Quality Level200
shipped indry ice
species reactivityhuman
storage temp.−20°C
technique(s)western blot: 1:500-1:1,000
UniProt accession no.P17213
Est. Dispatch/Availability