Application

Rabbit Anti-HOXA2 antibody can be used for western blot applications at a concentration of 0.5µg/ml.

Biochem/physiol Actions

In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development.HOXA2 is a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiateon. HOXA2 may be involved in the placement of hindbrain segments in the proper location along the anterior-posterior axis during development.In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. The encoded protein may be involved in the placement of hindbrain segments in the proper location along the anterior-posterior axis during development.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

HOXA2 is a homeobox gene that may modulate the expression, morphogenesis, and differentiation of developmental genes. Mouse Hoxa1 is known to regulate the patterning of early hindbrain.Rabbit Anti-HOXA2 antibody recognizes rabbit, bovine, canine, chicken, human, mouse, and rat HOXA2.

Immunogen

Synthetic peptide directed towards the middle region of human HOXA2

Physical form

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Sequence

Synthetic peptide located within the following region: GALLEREGYTFQQNALSQQQAPNGHNGDSQSFPVSPLTSNEKNLKHFQHQ