Analysis Note

ControlMouse cochlear tissue lysate

Application

Immunohistochemistry Analysis: A representative lot was used by an independent laboratory in mouse cochlear tissue. (Zheng, J., et al. (2011).PNAS. 108(10):4218–4223.)

Immunofluorescence Analysis: A representative lot was used by an independent laboratory in mouse cochlear tissue. (Zheng, J., et al. (2011).PNAS. 108(10):4218–4223.)

Research CategoryNeuroscience

Research Sub CategorySensory & PNS

This Anti-CEA cell adhesion molecule 16 (Ceacam16) Antibody is validated for use in Western Blotting, IHC, Immunofluorescence for the detection of CEA cell adhesion molecule 16 (Ceacam16).

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

Carcinoembryonic antigen-related cell adhesion molecule 16, also known as CEA cell adhesion molecule 16 (Ceacam16), is a novel adhesion protein that has been found in cochlear hair cells. It interacts with α-tectorin-interacting protein and may play a role in maintaining the tectorial membrane. Mutation of the Ceacam16 gene results in autosomal dominant nonsyndromic deafness (ADNSHL).

Immunogen

Linear peptide corresponding to mouse Ceacam16 monomers and dimers.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Physical form

Affinity purified

Purified rabbit polyclonal in buffer containing PBS with 0.05% sodium azide.

Quality

Evaluated by Western Blot in mouse cochlear tissue lysate.

Western Blot Analysis: 1 µg/mL of this antibody detected Ceacam16 in 10 µg of mouse cochlear tissue lysate.

Storage and Stability

Stable for 1 year at 2-8°C from date of receipt.

Target description

~55-250 kDa observed. This protein has been shown to detect monomers and dimers. (Zheng, J., et al. (2011).PNAS. 108(10):4218–4223.)