Analysis Note

ControlPANC-1 cell lysate

Application

Research Sub CategoryTranscription Factors

Immunohistochemistry Analysis: A 1:1,000 dilution from a representative lot detected MNX1 in human pancreas and mouse cerebral cortex tissues.

Research CategoryNeuroscience

Anti-MNX1 (HB9) Antibody detects level of MNX1 (HB9) & has been published & validated for use in Western Blotting & IHC.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

Motor neuron and pancreas homeobox protein 1 (MNX1) is a transcription factor that is predominantly expressed in lymphoid and pancreatic tissues. It is involved in the development and function of the pancreas. Abnormal expression of MNX1 results in an autosomal dominant condition known as Currarino syndrome.

Immunogen

KLH-conjugated linear peptide corresponding to human MNX1.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Physical form

Affinity purified

Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Quality

Evaluated by Western Blot in PANC-1 cell lysate.

Western Blot Analysis: 0.5 µg/mL of this antibody detected MNX1 in 10 µg of PANC-1 cell lysate.

Specificity

Other homologies: Zebrafish (94% sequence homology) and Xenopus (89% sequence homology).

This antibody recognizes a portion of the Homeobox DNA binding domain.

Storage and Stability

Stable for 1 year at 2-8°C from date of receipt.

Target description

~50 kDa observed. An uncharacterized band may appear at ~48 kDa in some lysates.