A6770-10MG Display Image

Methotrexate hydrate, >=98% (HPLC), powder

Code: A6770-10MG D2-231

Application

Potent inhibitor of dihydrofolate reductase and agent for antitumor studies. Use to inhibit dihydrofolate reductase in DHFR-based protein expression systems. Also...


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£42.50 10MG
£51.00 inc. VAT

Application

Potent inhibitor of dihydrofolate reductase and agent for antitumor studies. Use to inhibit dihydrofolate reductase in DHFR-based protein expression systems. Also shows immunosuppressive effects in, e.g., rheumatoid arthritis.

Potent inhibitor of dihydrofolate reductase and agent for antitumor studies. Use to inhibit dihydrofolate reductase in DHFR-based protein expression systems. Also effective in treatment of pyrimethamine-resistant Plasmodium vivax malaria parasites.

assay≥98% (HPLC)
biological sourcesynthetic (organic)
color, yellow to very dark yellow to very dark orange
formpowder
Gene Informationhuman ... DHFR(1719)
InChI keyFPJYMUQSRFJSEW-ZOWNYOTGSA-N
InChI1S/C20H22N8O5.H2O/c1-28(9-11-8-23-17-15(24-11)16(21)26-20(22)27-17)12-4-2-10(3-5-12)18(31)25-13(19(32)33)6-7-14(29)30;/h2-5,8,13H,6-7,9H2,1H3,(H,25,31)(H,29,30)(H,32,33)(H4,21,22,23,26,27);1H2/t13-;/m0./s1
mp185-204 °C
Quality Level200
SMILES string[H]O[H].CN(Cc1cnc2nc(N)nc(N)c2n1)c3ccc(cc3)C(=O)N[C@@H](CCC(O)=O)C(O)=O
solubilityH2O: insoluble
storage temp.−20°C
Code
Description
Unit Size
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A6770-100MG
Unit:100MG
List Price: £171.00
Source:List Price
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A6770-1G
Unit:1G
List Price: £1,540.00
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A6770-25MG
Unit:25MG
List Price: £72.20
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A6770-500MG
Unit:500MG
List Price: £875.00
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Cas Number133073-73-1
Hazard Class6.1
Un Number1544
Pack GroupIII
This product has met the following criteria: