Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Albendazole may be used as a reference standard for the determination of albendazole and its major metabolites, albendazole sulphoxide and albendazole sulphone by high-performance liquid chromatography (HPLC) method in mice plasma.

Biochem/physiol Actions

Binds to tubulin and inhibits microtubule assembly.

General description

Chemical structure: benzimidazole

Albendazole is a benzimidazole derivative used for the treatment of human gastrointestinal helmintiasis. It inhibits microtubule and blocks the glucose uptake that causes depletion of glycogen stores and lowering formation of adinosine triphosphate (ATP) in the larval and adult stages of susceptible parasite.

Other Notes

Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. A4673.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.

Packaging

10 g in poly bottle