Application
Used in hybridoma formation applications as a selection agent.
Biochem/physiol Actions
Ribosylated and phosphorylated by the same pathway as natural purine bases; as the nucleotide, inhibits a variety of cellular processes involved in nucleic acid synthesis. Has a long history as an effective treatment of leukemia.
Legal Information
Hybri-Max is a trademark of Sigma-Aldrich Co. LLC
Reconstitution
Reconstitute contents of vial with 10 ml sterile cell culture medium. Stock solution is sufficient to prepare 500 ml medium. Final working concentration: 30 µM 2-amino-6-mercaptopurine.
This product has met the following criteria: