A4188-5MG Display Image

N-Acetyl-Ile-Glu-Thr-Asp-7-Amido-4-methylcoumarin, >=97% (HPLC), powder

Code: A4188-5MG D2-231

Amino Acid Sequence

NAc-Ile-Glu-Thr-Asp-AMC

Application

Fluorogenic substrate for caspase 8 and granzyme B.

£414.82 5MG
List Price

SMILES stringCC[C@H](C)[C@H](NC(C)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(O)=O)C(=O)Nc1ccc2C(C)=CC(=O)Oc2c1
Quality Level200
InChI1S/C31H41N5O12/c1-6-14(2)26(32-17(5)38)30(46)34-20(9-10-23(39)40)28(44)36-27(16(4)37)31(47)35-21(13-24(41)42)29(45)33-18-7-8-19-15(3)11-25(43)48-22(19)12-18/h7-8,11-12,14,16,20-21,26-27,37H,6,9-10,13H2,1-5H3,(H,32,38)(H,33,45)(H,34,46)(H,35,47)(H,36,44)(H,39,40)(H,41,42)/t14-,16+,20-,21-,26-,27-/m0/s1
colorwhite
formpowder
assay≥97% (HPLC)
Gene Informationhuman ... CARD8(22900), CASP8(841), CASP8AP2(9994), CFLAR(8837), GZMB(3002)

mouse ... CFLAR(117279), GZMB(171528)

rat ... CASP8(12370), CFLAR(12633), GZMB(14939), RGD1561819(502004), RGD1562700(502007)

storage temp.−20°C
InChI keyZYTCBVQZQSFKHQ-HGZCCCDHSA-N
solubilityDMSO/DMF: 1 mg/mL