A4142-250MG Display Image

Azaserine, >=98% (TLC)

Code: A4142-250MG D2-231

Application

Used in cell culture for the selection of HGPRT revertants.

Biochem/physiol Actions

Azaserine is an antibiotic and antifungal; it may...

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£1,060.00 250MG
List Price

Application

Used in cell culture for the selection of HGPRT revertants.

Biochem/physiol Actions

Azaserine is an antibiotic and antifungal; it may also act as a tumor inducer. It is a structural analog of glutamine and competes with glutamine in binding to enzymes involved in purine biosynthesis. Azaserine inhibits purine biosynthesis by covalently reacting with cysteine residues in the enzyme active sites, such as in formylglycinamide ribonucleotide amidotransferase and PRPP amidotransferase. Azaserine can induce DNA damage via the formation of carboxymethylated bases and O6-methylguanine. Secretion of exo-1,3-ß-glucanase and germ-tube formation of Candida albicans were inhibited by azaserine.

General description

Chemical structure: amino acid derivatives

Packaging

50, 250 mg in glass bottle

antibiotic activity spectrumfungi
InChI1S/C5H7N3O4/c6-3(5(10)11)2-12-4(9)1-8-7/h1,3H,2,6H2,(H,10,11)/t3-/m0/s1
Mode of actionenzyme | inhibits
InChI keyMZZGOOYMKKIOOX-VKHMYHEASA-N
formpowder
coloroff-white to yellow-green
assay≥98% (TLC)
storage temp.−20°C
SMILES stringN[C@@H](COC(=O)C=[N+]=[N-])C(O)=O
Quality Level100

Code
Description
Unit Size
List Price
Qty
A4142-50MG
Unit:50MG
List Price: £264.00
Source:List Price
ADD
Cas Number115-02-6
Hazard Class6.1
Un Number3462
Pack Group3