Application

1,2-dimyristoyl-sn-glycero-3-ethylphosphocholine (14:0 EPC (Cl Salt)) is suitable for use in liposome formulations.

Biochem/physiol Actions

Synthetic cationic lipids serve as non-viral gene delivery agents. Change in the hydrocarbon chain of phosphatidylcholine (PC) derivatives affects transfection efficiency. 1,2-dimyristoyl-sn-glycero-3-ethylphosphocholine (14:0 EPC) aids in hydration during the formation of liposomes.

General description

1,2-dimyristoyl-sn-glycero-3-ethylphosphocholine (14:0 EPC) is an acyl cationic lipid. O-alkyl phosphatidylcholines constitute the first chemically stable tri-esters of biological lipid structures and the first cationic derivatives of phospholipids consisting entirely of biological metabolites linked with ester bonds. The lipid has low toxicity and is biodegradable.

Packaging

5 mL Clear Glass Sealed Ampule (890701P-10mg)

5 mL Clear Glass Sealed Ampule (890701P-25mg)