Application
Sphinganine (d18:0) has been used:as a standard in liquid chromatography tandem mass spectrophotometry for the quantification of epidermal ceramidesas a medium supplement to test its effect on growth of yeast cellsin the preparation of bovine serum albumin lipid complex to investigate its effect on non-lysosomal - glucosylceramidase β2 (GBA2) inhibition
Biochem/physiol Actions
Sphinganine (d18:0) levels are not altered in hereditary sensory neuropathy type 1 cells. Accumulation of d18:0 is observed in tumor hypoxia. It is useful as a biomarker for studying microbial diversity.
General description
Sphinganine (d18:0) is a substrate for the enzyme ceramide desaturase. It is synthesized indirectly due to the interconversion of supplemented glycine to serine. Sphinganine (d18:0) is catabolized to ceramide.
Packaging
5 mL Amber Glass Screw Cap Vial (860498P-100mg)
5 mL Amber Glass Screw Cap Vial (860498P-25mg)
5 mL Amber Glass Screw Cap Vial (860498P-10mg)
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