Application

18:1 PI(11)P (1,2-dioleoyl-sn-glycero-3-phospho-(1′-myo-inositol-5′-phosphate) (ammonium salt)) has been used in protein−lipid overlay assay. It may be used in liposome preparation and in liposome preparation for liposome pull-down experiments.

Biochem/physiol Actions

Phosphatidylinositol 5-phosphate (PI5P) is known to control chromatin organization and gene expression. It can also act as a coordinator of actin cytoskeleton, membrane trafficking and signaling. It participates in autophagy.

General description

18:1 PI(11)P (1,2-dioleoyl-sn-glycero-3-phospho-(1′-myo-inositol-5′-phosphate)) is an ammonium salt of modified lipid. Approximately 0.5% of total phosphoinositides (PI) in mammalian cells consists of PI5P.

Inositol phospholipid species are membrane-bound signaling molecules that have been implicated in almost all aspects of cellular physiology, including cellular growth, metabolism, proliferation, and survival.

Packaging

2 mL Amber Serum Vial with Stopper and Crimp Cap (850152P-100ug)

2 mL Amber Serum Vial with Stopper and Crimp Cap (850152P-500ug)