Application

Takasago Ligands and Complexes for Asymmetric Reactions

Catalyst involved in studies of the role of excess phosphine ligand in enantioselective conjugate addition of ethylmagnesium bromide and α,β-unsaturated esterReactant serving as a precursor for: Catalysts used for reductive amination of ketones Rh(I)-catalyst for hydrogenation of acetamidoacrylic acid derivatives Chiral platinum catalysts for asymmetric Baeyer-Villiger oxidation of cyclic ketones CuI-Tol-BINAP catalysts for enantioselective Michael reactions of Grignard reagents to unsaturated esters BINAP Pt Dications for cation trapping

(R)-T-BINAP complexes derived from rhodium precursors are used for the asymmetric hydroformylation of vinyl acetate. It may be employed as chiral catalyst for allylation of N-tosyl α-imino esters.

General description

BINAP is based on a bis naphthalene backbone with different phosphine derivatives. 2,2′-bis(di-p-tolylphosphino)-1,1′-binaphthyl (p-Tol-BINAP)·AgF complex catalyzed asymmetric Mukaiyama-type aldol reaction is reported.

Legal Information

Sold in collaboration with Takasago for research purposes only.

Packaging

100, 500 mg in amber glass bottle