Biochem/physiol Actions

Cell permeable: no

Reversible: no

Product does not compete with ATP.

Target IC₅₀: 100 nM-100 µM as Cl-channel blocker

Primary TargetCl_- channel blocker

General description

Potent Cl^– channel blocker (IC₅₀ = 100 nM-100 µM), depending on channel subtype and assay method. Inhibits cyclooxygenase (IC₅₀ = 8 µM).

Potent Cl^- channel blocker (IC₅₀ = 100 nM-100 µM), depending on channel subtype and assay method. Inhibits cyclooxygenase (IC₅₀ = 8 µM).

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Other Notes

Illek, B., et al. 1992. Am. J. Physiol.263, C644.Kirk, K., et al. 1992. J. Biol. Chem.267, 23475.Breuer, W., et al. 1989. Biochem. Biophys. Res. Commun.163, 398.Wangermann, P., et al. 1986. Pflugers Arch.407, S128.

Packaging

10 mg in Plastic ampoule

Warning

Toxicity: Standard Handling (A)