46121-25MG-F Display Image

Resorufin ethyl ether, suitable for fluorescence, >=95% (UV)

Code: 46121-25MG-F D2-231

Application

7-Ethoxyresorufin (7-ER) is a substrate used in environmental toxicology studies to monitor ethoxyresorufin-O-deethylase catalytic activity in the EROD assay. The...


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£1,480.00 25MG
£1,776.00 inc. VAT
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Application

7-Ethoxyresorufin (7-ER) is a substrate used in environmental toxicology studies to monitor ethoxyresorufin-O-deethylase catalytic activity in the EROD assay. The EROD assay monitors the induction of the xenobiotic-metabolizing enzyme cytochrome P-450 (CYP) 1A1 and is a widely used biomarker for exposure of wildlife to substances that bind the aryl hydrocarbon (Ah) receptor. It provides evidence of receptor-mediated induction of cytochrome P450-dependant monooxygenases (the CYP1A subfamily specifically) by xenobiotic chemicals.

Other Notes

Dealkylase substrate for the microfluorimetric analysis of microsomal cytochrome P-450

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

assay≥95% (UV)
fluorescenceλex 571 nm; λem 585 nm in dealkylase(lit.), λex 464 nm; λem 540 nm in methanol(lit.)
formsolid
InChI keyZOSYTBPPLWBBKM-UHFFFAOYSA-N
InChI1S/C23H14F5NO4.C14H11NO3/c24-17-18(25)20(27)22(21(28)19(17)26)33-16(30)9-29-23(31)32-10-15-13-7-3-1-5-11(13)12-6-2-4-8-14(12)15;1-2-17-10-4-6-12-14(8-10)18-13-7-9(16)3-5-11(13)15-12/h1-8,15H,9-10H2,(H,29,31);3-8H,2H2,1H3
mp223-225 °C (lit.)
Quality Level100
SMILES stringCCOc1ccc2N=C3C=CC(=O)C=C3Oc2c1.Fc4c(F)c(F)c(OC(=O)CNC(=O)OCC5c6ccccc6-c7ccccc57)c(F)c4F
solubilityDMF: soluble, alcohols: soluble, DMSO: soluble
storage temp.2-8°C
suitabilitysuitable for fluorescence
Code
Description
Unit Size
List Price
Qty
46121-5MG-F
Resorufin ethyl ether, suitable for fluorescence, >=95% (UV)

Unit:5MG
List Price: £402.00
Source:List Price
ADD
Cas Number5725-91-7
This product has met the following criteria: