Application

Catalyst employed in the Sharpless Asymmetric Dihyroxylation of (E,E)- or (E,Z)-1,3-dienoates. Also used in the preparation of ß-hydroxy-γ-lactones from ß,γ-unsaturated esters.

AD-mix-α has been used in the asymmetric dihydroxylation (AD) step of synthesizing (+)-enantiomeric form of a potent anti-inflammatory methyl picolinate alkaloid from methyl 5-bromopicolinate.

Reagent for Sharpless Asymmetric Dihydroxylation.

Components

Mixture contains: (DHQ)₂PHAL (Cat. No. 392723) 0.0016 molePotassium carbonate, powder 0.4988 molePotassium ferricyanide 0.4988 molePotassium osmate dihydrate 0.0007 mole

General description

Contains chiral ligand (DHQ)₂PHAL

Packaging

10, 50, 250 g in glass bottle