Full length, recombinant, human Plk2 fused at the N-terminus to GST and expressed in S. frugiperda insect cells using a baculovirus expression system. Plk2 is a G1 specific kinase that is specifically detected in brain, heart, and lung. Plk2 expression increases in the presence of DNA-damaging agents. The active kinase is useful for the study of Plk2 regulation and inhibitor screening.
TWEEN is a registered trademark of Croda International PLC
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Eckerdt, F., et al. 2005. Oncogene24, 267.Warnke, S., et al. 2004.Curr Biol.14, 1200.
10 µg in Plastic ampoule
Please refer to vial label for lot-specific concentration.
In 100 mM NaCl, 25 mM Tris-HCl, 3 mM DTT, 50% glycerol, 0.05% Tween®-20 detergent, pH 8.0.
Following initial thaw, aliquot and freeze (-70°C).
One unit is defined as the amount of enzyme that will phosphorylate 1 pmol SER/THR 16 substrate per min at 30°C, pH 7.5.
Toxicity: Standard Handling (A)