205548-500GM Display Image

Caffeine

Code: 205548-500GM D2-231

Biochem/physiol Actions

Primary TargetPotent central nervous system stimulant

Cell permeable: no

Reversible: no

Product does not compete with ATP.


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Your Price
£108.00 500GM
£129.60 inc. VAT

Biochem/physiol Actions

Primary TargetPotent central nervous system stimulant

Cell permeable: no

Reversible: no

Product does not compete with ATP.

General description

Trimethylated xanthine that acts as a potent central nervous system stimulant. A nonselective phosphodiesterase inhibitor. At higher doses, produces tachycardia and interferes with the uptake and storage of Ca2+ by the sarcoplasmic reticulum in skeletal muscle. Prevents apoptosis and cell cycle effects induced by camptothecin and topotecan in HL-60 cells.

Trimethylated xanthine that acts as a potent central nervous system stimulant. At higher doses, produces tachycardia and interferes with the uptake and storage of Ca2+ by the sarcoplasmic reticulum in skeletal muscle. Prevents apoptosis and cell cycle effects induced by Camptothecin (Cat. No. 208925) and topotecan in HL-60 cells.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Other Notes

Zhen, W., and Vaugha, A. T. 1995. Radiat. Res.141, 170.Howell, L. L. 1993. Cancer Res.54, 4993.Traganos, F., et al. 1993. Cancer Res.53, 4613.Zahradnik, I., and Palade, P. 1993. Pflugers Arch. 424, 129.

Packaging

500 g in Glass bottle

Reconstitution

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Warning

Toxicity: Harmful (C)

assay≥99% (HPLC)
colorwhite
formsolid
InChI keyRYYVLZVUVIJVGH-UHFFFAOYSA-N
InChI1S/C8H10N4O2/c1-10-4-9-6-5(10)7(13)12(3)8(14)11(6)2/h4H,1-3H3
manufacturer/tradenameCalbiochem®
Quality Level100
shipped inambient
solubilitychloroform: 50 mg/mL
storage conditionOK to freeze
storage temp.10-30°C
Cas Number58-08-2
This product has met the following criteria: