General description

Nucleoside antibiotic that specifically inhibits protein synthesis in both prokaryotes and eukaryotes. Suitable for selection of cells carrying plasmids conferring blasticidin resistance. Blasticidin resistance is conferred by the blasticidin S deaminase gene (bsr) that converts blastisidin S to a nontoxic deaminohydroxy derivative.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Other Notes

Kimura, M., et al. 1994. Biochim. Biophys. Acta1219, 653.Kimura, M., et al. 1994. Mol. Gen. Genet.242, 121.Kojima, N., et al. 1994. J. Biol. Chem.269, 30451.Kudo, T., et al. 1994. J. Immunol. Methods177, 17.Sutoh, K. 1993. Plasmid30, 150.Izumi, M., et al. 1991. Exp. Cell Res.197, 229.Yamaguchi, H., et al. 1965. J. Biol. Chem.57, 667.Takeuchi, S., et al. 1958. J. Antibiot.11, 1.

Packaging

10 ml in Plastic Bag(s)

Physical form

Supplied at 10 mg/ml in 20 mM HEPES, pH 7.5.

Reconstitution

Following initial thaw, aliquot and freeze (-20°C).

Warning

Toxicity: Highly Toxic (H)