PLA0277-100UL Display Image

RABBIT ANTI-CUL1 ANTIBODY

Code: PLA0277-100UL D2-231

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to b...


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Your Price
£425.00 100UL

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Immunogen

The epitope recognized by PLA0277 maps to a region between residue 726 and 776 of human Cullin 1 using the numbering given in entry NP_003583.2 (GeneID 8454).

Other Notes

Cullin 1 (Cul1) is the core component of multiple cullin-RING-based SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. In the SCF complex, Cul1 serves as a rigid scaffold that organizes the SKP1-F-box protein and RBX1 subunits. Cul1 may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q13616]

Physical form

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide

accession no.NP_003583.2
antibody formaffinity purified immunoglobulin
antibody product typeprimary antibodies
biological sourcerabbit
Gene Informationrabbit ... Cul1(8454)
gradePowered by Bethyl Laboratories, Inc.
Quality Level100
shipped inwet ice
species reactivitymouse, human
storage temp.2-8°C
technique(s)immunoprecipitation (IP): 2-10 µg/mg, western blot: 1:2,000- 1:10,000
UniProt accession no.Q13616
Quantity
Est. Dispatch/Availability