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The epitope recognized by PLA0289 maps to a region between residue 1248 and 1298 of human Akt Substrate of 160 kDa using the numbering given in entry NP_055647.2 (GeneID 9882).
The Akt substrate of 160 kDa (AS160) is a substrate of Akt kinase activity and is a GTPase activating protein (GAP) for Rab GTPases. AS160 is encoded by the TBC1D4 (TBC1 domain family, member 4) gene.
Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide